The parahippocampal cortex and hippocampus are brain structures known to be involved in memory. However, the unique contribution of the parahippocampal cortex remains unclear. The current study investigates memory for object identity and memory of the configuration of objects in patients with small thermo-coagulation lesions to the hippocampus or the parahippocampal cortex. Results showed that in contrast to control participants and patients with damage to the hippocampus leaving the parahippocampal cortex intact, patients with lesions that included the right parahippocampal cortex (...) (RPH) were severely impaired on a task that required learning the spatial configuration of objects on a computer screen; these patients, however, were not impaired at learning the identity of objects. Conversely, we found that patients with lesions to the right hippocampus (RH) or left hippocampus (LH), sparing the parahippocampal cortex, performed just as well as the control participants. Furthermore, they were not impaired on the object identity task. In the functional Magnetic Resonance Imaging (fMRI) experiment, healthy young adults performed the same tasks. Consistent with the findings of the lesion study, the fMRI results showed significant activity in the RPH in the memory for the spatial configuration condition, but not memory for object identity. Furthermore, the pattern of fMRI activity measured in the baseline control conditions decreased specifically in the parahippocampal cortex as a result of the experimental task, providing evidence for task specific repetition suppression. In summary, while our previous studies demonstrated that the hippocampus is critical to the construction of a cognitive map, both the lesion and fMRI studies have shown an involvement of the RPH for learning spatial configurations of objects but not object identity, and that this takes place independent of the hippocampus. (shrink)

Christian miller invites further clarification about the relationship between accountability and autonomy. Whereas embracing accountability to others for one’s responsibilities in those relationships emphasizes relationality, autonomy accents the individual’s own capacities to exhibit agency in enacting one’s decisions. Accordingly, we theorize that relational capacities for empathic concern and perspective-taking are especially important in the virtue of accountability. The capacity for self-regulation may serve both one’s autonomous pursuits and accountability for carrying out one’s responsibilities...

“Free Will” is a philosophical term of art for a particular sort of capacity of rational agents to choose a course of action from among various alternatives. Which sort is the free will sort is what all the fuss is about. (And what a fuss it has been: philosophers have debated this question for over two millenia, and just about every major philosopher has had something to say about it.) Most philosophers suppose that the concept of free will is very (...) closely connected to the concept of moral responsibility. Acting with free will, on such views, is just to satisfy the metaphysical requirement on being responsible for one's action. (Clearly, there will also be epistemic conditions on responsibility as well, such as being aware—or failing that, being culpably unaware—of relevant alternatives to one's action and of the alternatives' moral significance.) But the significance of free will is not exhausted by its connection to moral responsibility. Free will also appears to be a condition on desert for one's accomplishments (why sustained effort and creative work are praiseworthy); on the autonomy and dignity of persons; and on the value we accord to love and friendship. (See Kane 1996, 81ff. and Clarke 2003, Ch.1.). (shrink)

Psychiatry is rapidly adopting digital phenotyping and artificial intelligence/machine learning tools to study mental illness based on tracking participants’ locations, online activity, phone and text message usage, heart rate, sleep, physical activity, and more. Existing ethical frameworks for return of individual research results (IRRs) are inadequate to guide researchers for when, if, and how to return this unprecedented number of potentially sensitive results about each participant’s real-world behavior. To address this gap, we convened an interdisciplinary expert working group, supported by (...) a National Institute of Mental Health grant. Building on established guidelines and the emerging norm of returning results in participant-centered research, we present a novel framework specific to the ethical, legal, and social implications of returning IRRs in digital phenotyping research. Our framework offers researchers, clinicians, and Institutional Review Boards (IRBs) urgently needed guidance, and the principles developed here in the context of psychiatry will be readily adaptable to other therapeutic areas. (shrink)

_The Sub ject of Con scious ness_ is a rich, strik ingly orig i nal and ambi tious work. It makes an impor tant and timely con tri bu tion to cur rent debates on a num ber of issues which over the last few years have been tak ing cen tre stage in the phi los o phy of mind: for exam ple, self-consciousness, selec tive atten tion and the nature of bodily aware ness. What makes this achieve ment (...) some what unusual, and all the more remark able, is that _The Sub ject of Con scious ness_ was pub lished thirty years ago (Evans, 1970). The reviews it received at the time ranged from the hos tile to the deri sory. (shrink)

This paper argues that Kierkegaard is not an irrationalist, but a "responsible fideist." Responsible fideism attempts to answer two important philosophical questions: "Are there limits to reason?" and "How can the limits of reason be recognized?" Kierkegaard's account of the incarnation as "the absolute paradox" does not see the incarnation as a logical contradiction, but rather functions in a way similar to a Kantian antimony. Faith in the incarnation both helps us recognize the limits of reason and also to a (...) degree overcomes those limits. /// O artigo defende que Kierkegaard não é um irracionalista, mas antes um "fideísta responsável". Como tal, o "fideísmo responsável" tenta responder a duas questões fllosóficas particularmente importantes: "Existem limites para a razão?" e "Como podem os limites da razão ser reconhecidos?" Na sua interpretação da incarnação como "paradoxo absoluto", Kierkegaard não interpreta a incarnação como uma contradição lógica, mas antes a vê funcionando de um modo similar à antinomia kantiana. Fé na incarnação ajuda-nos não só a reconhecer os limites da razão, mas também nos ajuda, pelo menos até um certo ponto, a ultrapassar estes limites. (shrink)

Communication and Conflict Management Training for Clinical Bioethics Committees Content Type Journal Article Pages 341-349 DOI 10.1007/s10730-009-9116-7 Authors Lauren M. Edelstein, Johns Hopkins Medicine’s Howard County General Hospital 5755 Cedar Lane Columbia MD 21044 USA Evan G. DeRenzo, Washington Hospital Center Center for Ethics 110 Irving St Washington, D.C. NW 20010 USA Elizabeth Waetzig, Change Matrix Inc. 485 Maylin St. Pasadena CA 91105 USA Craig Zelizer, Georgetown University Department of Government 3240 Prospect St. Washington, D.C. NW 20057 USA Nneka O. (...) Mokwunye, Washington Hospital Center Center for Ethics 110 Irving St Washington, D.C. NW 20010 USA Journal HEC Forum Online ISSN 1572-8498 Print ISSN 0956-2737 Journal Volume Volume 21 Journal Issue Volume 21, Number 4. (shrink)

Faced with troubling professional decisions in his long and successful career as a psychiatrist, M. O'C. Drury turned for direction to the philosophical work of his teacher and friend, Ludwig Wittgenstein. Of particular concern to Drury were the situations in which psychiatrists were expected to differentiate between instances of madness that were religious in form and instances of genuine religious experience that, for their oddity, landed believers in psychiatric consulting rooms. In this essay we consider the special orientation Wittgenstein's philosophy (...) gave Drury, for example the way in which Drury came to understand how even his search for a principle of differentiation between madness and religion was misleading and contrary to his own practice—how it involved ‘sitting back in a cool hour and attempting to solve this problem as a pure piece of theory. To be the detached, wise, external critic’ and not see himself and his own manner of life ‘as intimately involved in the settlement of this question.’. (shrink)

Using covariant derivatives and the operator definitions of quantum mechanics, gauge invariant Proca and Lehnert equations are derived and the Lorenz condition is eliminated in U(1) invariant electrodynamics. It is shown that the structure of the gauge invariant Lehnert equation is the same in an O(3) invariant theory of electrodynamics.

I agree with Oaksford & Chater (O&C) that human beings resemble Bayesian reasoners much more closely than ones engaging standard logic. However, I have many problems with their framework, which appears to be rooted in normative rather than ecological rationality. The authors also overstate everyday rationality and neglect to account for much relevant psychological work on reasoning.

From the back cover: This book offers a collection of papers on focal themes in truth research, including minimalism, pragmatism and pluralism, and philosophical logic. It further provides valuable hindsight with contemporary perspectives on the works of Frege, Wittgenstein, Ramsey, Strawson, and Evans on truth, and it features recent discussions on the role and value of truth in politics and political discourse. The collection is based on groundbreaking presentations hosted by the Virtual International Consortium for Truth Research (VICTR), including (...) talks given at the TRUTH 20/20 conference. -/- The volume features exclusive transcriptions of panel discussions on truth and factuality with Huw Price, Douglas Edwards, Cheryl Misak, and Amie Thomasson, and on truth and polarization with Michael Lynch, Maria Baghramian, and Cailin O’Connor. It includes the transcript of a televised 1973 conversation between Peter Strawson and Gareth Evans. And the volume features new contributions from established and early career researchers in the field. Anyone interested in the nature and value of truth will find this volume to be indispensable. (shrink)

Certain proximities between two distinguished but very dissimilar contemporaries, Quintilian and Tacitus, may be stated. Contemporary they were, though the former, born probably a little before A.D. 40, was older by about twenty years. Both were from outside Rome, Quintilian certainly of provincial, Spanish, origin, Tacitus very probably from one of the Galliae, yet both exemplars of Romanitas.

ABSTRACT This article focuses on the limitations of four major critiques of the work of Leavis made by Kevin Harris. It is argued that (1) Leavis's procedure of working with the concrete and particular and (2) the context within which he worked, dominated by the exponents of modernism, are glossed over by Harris so that Leavis's insights are not given due weight. Furthermore, Harris overlooks the significance of an Aristotelian perspective to Leavis's concern for value and thus underestimates literature's role (...) in furthering our understanding of what it is to flourish. (shrink)

No one who attended the 2010 national public health law conference hosted by the Public Health Law Association and the American Society of Law, Medicine & Ethics could miss the sense of excitement and momentum. The revival of this annual public health law meeting, with the support of the Robert Wood Johnson Foundation, the energetic leadership of the PHLA president and board, ASLME’s expert guidance, and a rousing address by Dr. Tom Frieden, Director of the Centers for Disease Control and (...) Prevention, symbolize the continued commitment of a wide range of important individuals and institutions to the proposition that law is of substantial importance to public health. But there is more than just symbolism to be excited about. CDC’s public health law program continues to champion efforts to promote the use and understanding of law as a public health tool. (shrink)